REPR200-0315: Genetics, Epigenetics, and Stem Cells
In some of the course Real Time Sessions the lecture will be predominantly audio
while in others the lecture will be predominantly text.
Enrollment is closed.
Instructor(s):
Jennifer G. Barrett, DVM, Ph.D., Diplomate ACVS, Diplomate ACVSMR
Jerold S. Bell, DVM
Kathleen Cavanagh, Honors B.Sc., DVM, MET
Michael Golding, B.Sc., Ph.D.
Course Open: March 10-April 17, 2015
Real Time Sessions (RTS): Tuesdays, March 17, 24, 31, and April 7, 2015; 8:00-10:00 pm ET (US)
Course RTS Times in Your Area:
World Clock Converter
Practice Sessions: In order to prepare you for a successful experience
in your CE course, we request you attend a Practice Session prior to the first
Real Time Session. Please arrive promptly at the start time; each Practice Session
is up to 1 hour in length.
For more information, please visit the
CE Practice Area.
*Some of the instructors for this course will be using audio which will require you to have a headset or speakers to listen.
If you have any concerns regarding your computer's audio capabilities, please be sure to attend
one of the Practice Sessions.
Level and Prerequisites:
This
basic course will be open to veterinarians
actively interested in genetics as applied to everyday veterinary practice.
The scope of the course will not provide training in application of the new technology
(such as stem cells) but act to introduce the generalist to the field.
VIN CE Course: Open to veterinarians.
This course is approved by RACE for veterinarians.
The Veterinary Information Network (VIN) is RACE Provider #22.
Course Description:
Genetics, Epigenetics, Stem Cells - these are all rapidly evolving areas of biotech science
that sometime seem magical because of the pace of innovation. Epigenetics is an exciting
newer field that deals with the controllers of genetic code expression. Stem cell therapy
is a still-evolving treatment modality that takes advantage of the primitive cell code
that can be expressed to achieve differentiation, in order to produce a regenerative therapy.
Genetic counseling and testing, and breed-related disorders are clinical practice areas
that have changed rapidly over the last few years.
We will provide practical updates that can impact the way you practice veterinary medicine,
both now, and moving forward! Though epigenetics is still "in the incubator", developments
here are expected to revolutionize medicine (development, pharmacology, nutrition, and
individualized patient care).
The more we test the more we find conditions that are genetic related. Epigenetics is an
explanation for differing gene expression related to internal and external environmental
factors. Stem cells are providing an exciting new direction in regenerative medicine.
This course consists of four (4) 2-hour Real Time Session, supplemental library materials,
interactive message board discussions, and a mandatory end-of-course test.
Successful completion (scoring 80% or better) on the end-of-course test is required
to earn a certificate of completion for the course.
To learn more about the requirements for earning a CE certificate, please refer to
Receiving Your CE Credit and Course Completion Certificate.
*The lecture portion of real time sessions 2-4 will be audio presentations, please be prepared to listen.
Upon completion of this course, the participant should be able to
- identify and apply current genetic or genetic-related tests for common conditions
in companion animals.
- develop and present a mini case that shows how counseling and/or testing
was applied (or could be applied), via sharing experiences in the forum for
the course, and review cases provided by the speakers to see examples of how
these tools are applied.
- assess and discuss ethical implications of application of these technologies.
- critically review new developments in the fields based upon a review of common terms,
basic theory, and review of selected examples of research from the primary literature.
Course Materials: Course materials will be available
in the course library prior to each Real Time Session.
Required Textbook(s): There is no required textbook for this course.
Recommended Textbook(s):
- J. S. Bell, K. E. Cavanagh, L. P. Tilley, F. C. W Smith (2012).
Veterinary Medical Guide to Dog and Cat Breeds. Teton New Media.
ISBN-13: 978-1591610021
Available in the VIN bookstore:
http://store.vin.com/9781591610021
Remember to login to receive VIN your membership discount.
About the Instructors:
Jennifer (Jen) Barrett is the Theodora Ayer Randolph Professor at
the Marion duPont Scott Equine Medical Center at Virginia Tech. She is a Diplomate
of the American College of Veterinary Surgeons and the American College of Veterinary
Sports Medicine and Rehabilitation. She is a founder and currently Chair of the North
American Veterinary Regenerative Medicine Association. She manages the Regenerative
Medicine Service at EMC, and her research interests include stem cell and platelet rich
plasma therapy, and healing of the cartilage, tendon and ligament tissues. She applies
her regenerative medicine skills in horses and dogs primarily.
Jerold (Jerry) Bell is an internationally-known clinical genetics
consultant and lecturer. He is also a Clinical Associate Professor at Tufts, and owns
Freshwater Veterinary Hospital. As a breeder of Gordon Setters, he has been able to
apply the concepts published in the 2012 book published by Teton New Media with Cavanagh,
Smith and Tilley. He is an active volunteer in the OFA and AKC. He lectures widely
on genetic counseling and genetics. He is the coordinator for the Tufts Canine and
Feline Breeding & Genetics conference. Proceedings of these conferences can be
found through the VIN service.
Kathleen (Kathy) Cavanagh has been a veterinarian for 29 years.
She has a second parallel career in educational technology, instructional design,
writing and editing. Her projects have been online, print and disc-based, and for
both veterinary professionals and the public. For the last seven years she has been
an online nutrition instructor for University of Guelph/Equine Guelph, and is a
part-time practitioner and was a feline-exclusive practitioner for 10 years.
The 2012 Teton New Media book co-authored with Bell, Smith and Tilley reflects her
ongoing clinical interest in epigenetics/genetics and metabolic disturbances,
especially relating to nutrition.
Michael Golding is an Assistant Professor at Texas A&M.
His research interests include fetal physiology and epigenetic programming.
His special interest is in the epigenetics of early mammalian development and the
impact of the environment and nutrients have on programming. He has published articles
about this area of research in multiple species including dogs, and is part of the
eight-faculty member TAMU veterinary team researching exciting new developments in
genetics, epigenetics, and evolving diagnostic tests for inherited disease and traits.
Course Outline:
Week 1 (Real Time Session March 17, 2015):
Basic Concepts of Genetics/Epigenetics/Stem Cell
Instructor(s): Dr. Kathleen Cavanagh
Format: Text
Recommended Reading (prior to March 17 Real Time Session):
Veterinary Medical Guide to Dog and Cat Breeds;
Read Genetic Concepts pages 2-4,
Look over Appendices A - C, pages 591-644
Content:
We will focus on those concepts that the learner will need in order to understand
the next three units.
We will emphasize those topics that a practicing veterinarian would need to be apprised
of in order to counsel their clients, effectively test for diseases using gene-based
or related testing, and to gain an appreciation of newer developments in the biotech
field such as epigenetics and applications for stem cell therapy in regenerative medicine.
We will have a brief discussion of critical analysis of literature - hype and popular
press, different study designs, still subject to further research, bioethics.
Week 2 (Real Time Session March 24, 2015):
Genetic Testing and Counseling, and Breed-Related Disorders
Instructor(s): Dr. Jerold Bell
Format: Audio
Recommended Reading (prior to March 24 Real Time Session):
Veterinary Medical Guide to Dog and Cat Breeds;
Review Genetic Concepts pages 2-4,
Read Genetic Counseling and Management of Genetic Disease pages 5-8,
2 dog breed and 2 cat breed chapters of your choice,
Take a look at the OFA (www.offa.org),
CHIC (www.caninehealthinfo.org),
iCatCare (http://www.icatcare.org/advice/cat-breeds) and
WSAVA Genetic Testing (
http://research.vet.upenn.edu/DNAGeneticsTestingLaboratorySearch/tabid/7620/Default.aspx)
websites.
Content:
There are many common issues across and between breeds and species.
We will discuss important genetic tests, when they should be used and professional
counseling in your practice. Clinically important disorders that we see regularly
in practice will be highlighted. Case examples of use of testing and counseling
will be explored.
Week 3 (Real Time Session March 31, 2015):
Stem Cells/Regenerative Medicine
Instructor(s): Dr. Jennifer Barrett
Format: Audio
Content:
Stem cell therapy brings renewed hope for cures for a variety of medical problems
in human and veterinary patients. However, the field of stem cell biology is very
complex and ach disease process or injury requires years of thorough research before
clinically proven stem cell therapies are established. Along with the new hope stem
cell therapy brings, there is some degree of hype in the media as well as from
veterinary commercial entities offering "stem cell therapy" that may or may not
represent safe and efficacious treatments. This lecture will review the basics of
stem cell biology relevant to currently available therapies. This includes a
primer on the commercially available "stem cell" therapies, clinical indications
that are relevant and non-relevant for stem cell therapy, different types of stem
cell therapies, and what to expect for the future.
Week 4 (Real Time Session April 7, 2015):
Epigenetics
Instructor(s): Dr. Michael Golding
Format: Audio
Content:
This session will provide an introduction to the new active field of epigenetics
and how these new findings can be integrated into veterinary medicine.
- Epigenetics - The Big Picture
- Histones and Chromatin Structure
- DNA Methylation
- Developmental Programming
- Epigenetics and Disease
- Epigenetics and Development - Genotype does not equal phenotype
- Genomic Imprinting
- Epigenetic Therapies and Future Directions
CE Credits: 8
Tuition: Member $168 ($151 early bird special if enrolled by February 24, 2015)
Non-Member $266 ($239 early bird special if enrolled by February 24, 2015)
*To ensure participants are ready and prepared for classes,
enrollment will close on March 17, 2015 at 5 pm ET (USA)
or when the maximum number of participants is reached.
*For more information on how online CE works, see the
Participant Resource Center.
To Enroll:
Enrollment is closed.
- Enrollment qualifications: VIN CE courses are open to
VIN member and non-member veterinarians. Veterinarians enrolling in a VSPN CE course
must be a VIN member. Veterinary support staff must be a VSPN member to enroll in a
VSPN CE or a VIN CE course open to VSPN member enrollment.
- Each enrollee must be able to receive emails from @vspn.org
and @vin.com addresses. Email is our major form of communication with participants;
personal emails are highly recommended rather than clinic/hospital email addresses.
- Each person is individually responsible for his/her own registration.
To ensure that all information received is secure and correct, please do not enroll
for a course on behalf of another individual.
- For further assistance call 800-846-0028 ext. 797 or email
CEonVIN@vin.com.
Please include the course title, your full name, and contact information in your correspondence.
*Note:
"This course is approved for 8 continuing education credits in jurisdictions
which recognize AAVSB RACE approval; however participants should be aware that some
boards have limitations on the number of hours accepted in certain categories and/or
restrictions on certain methods of delivery of continuing education."
Call VIN CE at 800-846-0028 ext. 797 for further information.
(Attendees are encouraged to check with their licensing jurisdiction(s) for
information regarding recognition by their board).
Course withdrawal and refund policy: A complete refund of the paid course price will be
issued when your withdrawal request is received prior to the listed start date of the course.
If you wish to withdraw after the start date please contact the VIN office 800-846-0028 ext. 797
to discuss eligibility for a pro-rated refund.
* Note: To ensure rapid handling of your request for withdrawal, we recommend that you
call the VIN office at 800-846-0028 ext. 797.
*For more information on VIN's upcoming CE courses, check the
VIN Course Catalog.
The CE team:
Katherine James, DVM, PhD, DACVIM (SAIM)
VIN Education Coordinator
VIN CE Services:
CEonVIN@vin.com
800-846-0028 or 530-756-4881; ext. 797
or direct line to VIN/VSPN from the United Kingdom: (014522) 26154
or direct line to VIN/VSPN from Australia: 011 +61 26 145-2357
800.700.4636 | CEonVIN@vin.com | 530.756.4881 | Fax: 530.756.6035
777 West Covell Blvd, Davis, CA 95616
Copyright 2002, Veterinary Information Network, Inc.
|