NEUR100-0117: Seizure Management: Depolarization, Repolarization, and What we can do about it
Some of the lectures for this course will be presented in an audio format and others in a text format.
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Presenters:
Anne Elizabeth Katherman, DVM, MS, DACVIM/Neurology
Dawn Boothe, Phd, DVM, DACVIM/Internal Medicine, DACVCP
Course Open: January 11-February 18, 2017
Real Time Sessions (RTS): Wednesdays, January 18, 25, February 1, and 8, 2017; 9:30-11:30 pm ET (USA)
Course RTS Times in Your Area:
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Practice Sessions: In order to prepare you for a successful experience
in your CE course, we request you attend a Practice Session prior to the first
Real Time Session. Please arrive promptly at the start time; each Practice Session
is up to 1 hour in length.
For more information, please visit the
CE Practice Area.
*The presenters for this course will be using audio which will require you to have a headset or speakers to listen.
If you have any concerns regarding your computer's audio capabilities, please be sure to attend
one of the Practice Sessions.
Level and Prerequisites:
This
intermediate course will be open to veterinarians
actively interested in seizure management.
VIN CE Course: Open to veterinarians.
This course is approved by RACE for veterinarians. (RACE 22-28215)
Course Information:
The primary purpose of this course is to provide an in depth understanding
of how various anticonvulsants work and how to use this information
to make decisions regarding which anticonvulsant to use for a given patient
and when to alter the dose or change the drug. The course will include
a discussion of seizure pathophysiology, general principles of seizure management,
drug monitoring and a discussion of the most commonly used anticonvulsants
in the canine and feline species. Case examples will be provided to illustrate
the principles of seizure management. Management of patients with cluster
seizures and status epilepticus will be included and alternatives for
anticonvulsants which are currently difficult to obtain will be discussed.
The course will also include an overview of the diagnostic workup for
patients with secondary seizures.
Phenobarbital, Potassium Bromid, Zonisamide, Keppra, Keppra XR, Gabapentin,
Pregabalin, and Imepitoin will be discussed.
Week 1 (Real Time Session January 18, 2017):
Seizure Pathophysiology and Principles of Seizure Management
Presenter: Anne Elizabeth Katherman, DVM, MS, DACVIM/Neurology
Format: Text
Objectives: Upon completion of this session, the participant should be able to
- identify the major excitatory and inhibitory neurotransmitters.
- identify the location of action for each anticonvulsant.
- explain how each anticonvulsant works.
- list the important factors for judging anticonvulsant efficacy.
- list the principles for adding and discontinuing anticonvulsants.
Week 2 (Real Time Session January 25, 2017):
Introduction to Anticonvulsants and How They Work
Presenter: Dawn Boothe, Phd, DVM, DACVIM/Internal Medicine, DACVCP
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
- describe a general approach to drug management of epilepsy.
- relate abnormal neuronal physiology to seizure activity and anticonvulsant
drug mechanisms of action.
- relate key pharmacokinetic disposition of each of the anticonvulsant drugs
to safe and effective use, including a focus on:
- Rate and extent of volume of distribution and its relationship to onset of action.
- The role of hepatic metabolism in drug efficacy and safety and specifically.
- Site of potential drug- drug or drug-diet interactions and their effect
on drug efficacy and safety.
- The relationship of half-life and dosing interval to the design of the
dosing regimen and specifically:
- Whether or not the drug accumulates or fluctuates during a dosing interval.
- When monitoring can be implemented.
- Whether or not peak or trough samples should be collected for monitoring.
- How dosing regimens should be modified in the event of failure.
- identify clinically relevant adverse events for a specific set of anticonvulsants
and how they might be avoided, detected and treated.
- describe the role of therapeutic drug monitoring and "therapeutic range" in
the control of epilepsy in the individual patient.
Week 3 (Real Time Session February 1, 2017):
Case Based Seizure Management
Presenter: Anne Elizabeth Katherman, DVM, MS, DACVIM/Neurology
Format: Text
Objectives: Upon completion of this session, the participant should be able to
- choose an appropriate anticonvulsant and appropriate laboratory
and drug monitoring for a na�ve seizure patient with presumed
idiopathic epilepsy based on frequency of seizures, side effects
of medication, time to drug steady state, and cost of drug.
- choose appropriate drug and laboratory monitoring and additional
anticonvulsant medication for a poorly controlled seizure patient
on multiple anticonvulsants.
- take appropriate steps for a seizing patient with medical complications
or unacceptable drug side effects.
- recognize what may contribute to elevated anticonvulsant drug levels
and clinical signs of anticonvulsant drug toxicity and recommend
appropriate steps depending on the drug involved.
Week 4 (Real Time Session February 8, 2017):
Status Epilepticus and Secondary Seizures
Presenter: Anne Elizabeth Katherman, DVM, MS, DACVIM/Neurology
Format: Text
Objectives: Upon completion of this session, the participant should be able to
- understand the difference between cluster seizures and status epilepticus.
- develop knowledge of the anticonvulsant options for specific
treatment of cluster seizures.
- follow a logical approach to the treatment of status epilepticus
- recognise the signs of cerebral edema and the appropriate drugs
for attempting to counteract it.
- recognize those patients that are most likely to have secondary seizures
based on signalment, history, physical, neurological and
laboratory examination results.
- list the general categories of diseases which can cause secondary seizures.
Successful completion (scoring 80% or better) on the end-of-course test is required
to earn a certificate of completion for the course.
To learn more about the requirements for earning a CE certificate, please refer to
Receiving Your CE Credit and Course Completion Certificate.
Course Materials: Course materials will be available
in the course library prior to each Real Time Session.
Required Textbook(s): There is no required textbook for this course.
About the Presenters:
Anne Elizabeth Katherman serves as a Veterinary Information
Network neurology consultant. In addition she develops continuing education
courses on neurology topics for VIN, does research for the VIN Drug Formulary
and is the associate editor for the neurology chapters in the VIN online
textbook Associate. Dr. Katherman did her residency training at Purdue and
Auburn Universities. Dr. Katherman lives in Hampton, Virginia. Dr. Katherman
previously owned a Neurology and Neurosurgery specialty practice in Yorktown
and Virginia Beach, Virginia, worked in both specialty and general practices
in Washington DC, Maryland and Virginia and was an assistant professor at the
Virginia Maryland Regional College of Veterinary Medicine. She has served on
various ACVIM committees and has been a reviewer for the JACVIM.
Dawn Boothe joined the Auburn University College of Veterinary
Medicine in 2003. She received her B.S. degrees in Zoology (1977) and Veterinary
Medicine (1978), D.V.M. degree (1980), and M.S. degree in Physiology (1986) from
Texas A&M University. She continued her education with an internship in 1981 at
Auburn University's Small Animal Surgery and Medicine, then went back to Texas
A&M University, Small Animal Internal Medicine for her residency program in 1985.
Dr. Boothe completed her Ph.D. degree and fellowship in 1989 in the field of
Physiology (Clinical Pharmacology) at Texas A&M University. Dr. Boothe is a Diplomate
ACVIM (Internal Medicine) and Diplomate ACVCP (Clinical Pharmacology). Dr. Booth has
received the Distinguished Achievement Award in Teaching (University Level), May 1997,
and the Merck AgVet Award for Creativity in Teaching, July 1996, at Texas A&M University.
Currently, Dr. Booth is assisting in teaching Veterinary Pharmacology to second-year
veterinary students and is the Director of the Clinical Pharmacology Laboratory at
the Auburn University College of Veterinary Medicine.
Total CE Credit: 8
Tuition: Member $184 ($166 early bird special if enrolled by December 21, 2016)
Non-Member $288 ($259 early bird special if enrolled by December 21, 2016)
Prices are listed in US dollars.
*To ensure participants are ready and prepared for classes,
enrollment will close on January 11, 2017 at 5 pm ET (USA)
or when the maximum number of participants is reached.
*For more information on how online CE works, see the
Participant Resource Center.
To Enroll:
» Enroll Now
- Enrollment qualifications: VIN CE courses are open to
VIN member and non-member veterinarians. Veterinarians enrolling in a VSPN CE course
must be a VIN member. Veterinary support staff must be a VSPN member to enroll in a
VSPN CE or a VIN CE course open to VSPN member enrollment.
- Each enrollee must be able to receive emails from @vspn.org
and @vin.com addresses. Email is our major form of communication with participants;
personal emails are highly recommended rather than clinic/hospital email addresses.
- Each person is individually responsible for his/her own registration.
To ensure that all information received is secure and correct, please do not enroll
for a course on behalf of another individual.
- For further assistance call 800-846-0028 ext. 797 or email
CEonVIN@vin.com.
Please include the course title, your full name, and contact information in your correspondence.
"This program (22-28215) is approved by the AAVSB RACE to offer a
total of 8 CE Credits, with a maximum of 8 CE Credits being available to any individual
veterinarian.
This RACE approval is for the subject matter categories of:
Scientific,
using the delivery method of Interactive-Distance: (Web-based, Teleconference or Audio-Conference).
This approval is valid in jurisdictions which recognize AAVSB RACE; however, participants are
responsible for ascertaining each board's CE requirements."
Course withdrawal and refund policy: A complete refund of the paid course price will be
issued when your withdrawal request is received prior to the listed start date of the course.
If you wish to withdraw after the start date please contact the VIN office 800-846-0028 ext. 797
to discuss eligibility for a pro-rated refund.
* Note: To ensure rapid handling of your request for withdrawal, we recommend that you
call the VIN office at 800-846-0028 ext. 797.
*For more information on VIN's upcoming CE courses, check the
VIN Course Catalog.
Katherine James, DVM, PhD, DACVIM (SAIM)
VIN Education Coordinator
VIN CE Services:
CEonVIN@vin.com
800-846-0028 or 530-756-4881; ext. 797
or direct line to VIN/VSPN from the United Kingdom: 01 45 222 6154
or direct line to VIN/VSPN from Australia: 02 6145 2357
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